A strategic approach to [6,6]-bicyclic lactones: application towards the CD fragment of DHβE

We report an effective synthetic protocol to access [6,6]-bicyclic lactone moieties through a regio- and stereoselective intramolecular Mizoroki–Heck cross-coupling reaction followed by a 6π-electrocyclization. This method enabled the first synthesis of the elusive CD fragment of the Erythrina alkal...

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Detalles Bibliográficos
Autores principales: Jepsen, Tue Heesgaard, Glibstrup, Emil, Crestey, François, Jensen, Anders A, Kristensen, Jesper Langgaard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480346/
https://www.ncbi.nlm.nih.gov/pubmed/28684978
http://dx.doi.org/10.3762/bjoc.13.98

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480346/
https://www.ncbi.nlm.nih.gov/pubmed/28684978
http://dx.doi.org/10.3762/bjoc.13.98

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