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A strategic approach to [6,6]-bicyclic lactones: application towards the CD fragment of DHβE
We report an effective synthetic protocol to access [6,6]-bicyclic lactone moieties through a regio- and stereoselective intramolecular Mizoroki–Heck cross-coupling reaction followed by a 6π-electrocyclization. This method enabled the first synthesis of the elusive CD fragment of the Erythrina alkal...
Autores principales: | Jepsen, Tue Heesgaard, Glibstrup, Emil, Crestey, François, Jensen, Anders A, Kristensen, Jesper Langgaard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480346/ https://www.ncbi.nlm.nih.gov/pubmed/28684978 http://dx.doi.org/10.3762/bjoc.13.98 |
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