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A concise and practical stereoselective synthesis of ipragliflozin L-proline

A concise and practical stereoselective synthesis of ipragliflozin L-proline was presented starting from 2-[(5-iodo-2-fluorophenyl)methyl]-1-benzothiophene and 2,3,4,6-tetra-O-pivaloyl-α-D-glucopyranosyl bromide without catalyst via iodine–lithium–zinc exchange. The overall yield was 52% in three st...

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Detalles Bibliográficos
Autores principales:	Ma, Shuai, Liu, Zhenren, Pan, Jing, Zhang, Shunli, Zhou, Weicheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2017
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480354/ https://www.ncbi.nlm.nih.gov/pubmed/28684985 http://dx.doi.org/10.3762/bjoc.13.105

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