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Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy
Traditional genome-wide scans for positive selection have mainly uncovered selective sweeps associated with monogenic traits. While selection on quantitative traits is much more common, very few signals have been detected because of their polygenic nature. We searched for positive selection signals...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480811/ https://www.ncbi.nlm.nih.gov/pubmed/28640878 http://dx.doi.org/10.1371/journal.pgen.1006328 |