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Dexibuprofen prevents neurodegeneration and cognitive decline in APPswe/PS1dE9 through multiple signaling pathways
The aim of the present study is to elucidate the neuronal pathways associated to NSAIDs causing a reduction of the risk and progression of Alzheimer's disease. The research was developed administering the active enantiomer of ibuprofen, dexibuprofen (DXI), in order to reduce associated gastric...
Autores principales: | Ettcheto, Miren, Sánchez-López, Elena, Pons, Laura, Busquets, Oriol, Olloquequi, Jordi, Beas-Zarate, Carlos, Pallas, Merce, García, Maria Luisa, Auladell, Carme, Folch, Jaume, Camins, Antoni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480981/ https://www.ncbi.nlm.nih.gov/pubmed/28646794 http://dx.doi.org/10.1016/j.redox.2017.06.003 |
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