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HIV-Tat regulates macrophage gene expression in the context of neuroAIDS
Despite the success of cART, greater than 50% of HIV infected people develop cognitive and motor deficits termed HIV-associated neurocognitive disorders (HAND). Macrophages are the major cell type infected in the CNS. Unlike for T cells, the virus does not kill macrophages and these long-lived cells...
Autores principales: | Carvallo, Loreto, Lopez, Lillie, Fajardo, Jorge E., Jaureguiberry-Bravo, Matias, Fiser, Andras, Berman, Joan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481010/ https://www.ncbi.nlm.nih.gov/pubmed/28640909 http://dx.doi.org/10.1371/journal.pone.0179882 |
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