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Targeting breast cancer cells by MRS1477, a positive allosteric modulator of TRPV1 channels
There is convincing epidemiological and experimental evidence that capsaicin, a potent natural transient receptor potential cation channel vanilloid member 1 (TRPV1) agonist, has anticancer activity. However, capsaicin cannot be given systemically in large doses, because of its induction of acute pa...
Autores principales: | Nazıroğlu, Mustafa, Çiğ, Bilal, Blum, Walter, Vizler, Csaba, Buhala, Andrea, Marton, Annamária, Katona, Róbert, Jósvay, Katalin, Schwaller, Beat, Oláh, Zoltán, Pecze, László |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481018/ https://www.ncbi.nlm.nih.gov/pubmed/28640864 http://dx.doi.org/10.1371/journal.pone.0179950 |
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