New Diterpenoids from Clerodendranthus spicatus

Two new diterpenoids, neoorthosiphonones B and C (1 and 2), and one known diterpenoid, were isolated from the aerial parts of Clerodendranthus spicatus. Their structures including absolute configurations were determined by comprehensive spectroscopic analyses and X-ray crystallographic methods. No c...

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Detalles Bibliográficos
Autores principales: Li, Ya-Mei, Xiang, Bing, Li, Xiao-Zheng, Yan, Yong-Ming, Cheng, Yong-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481273/
https://www.ncbi.nlm.nih.gov/pubmed/28470482
http://dx.doi.org/10.1007/s13659-017-0128-8
Descripción
Sumario:Two new diterpenoids, neoorthosiphonones B and C (1 and 2), and one known diterpenoid, were isolated from the aerial parts of Clerodendranthus spicatus. Their structures including absolute configurations were determined by comprehensive spectroscopic analyses and X-ray crystallographic methods. No compound was found to inhibit fibronectin production at the concentration of 20 μM. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13659-017-0128-8) contains supplementary material, which is available to authorized users.

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