New Diterpenoids from Clerodendranthus spicatus

Two new diterpenoids, neoorthosiphonones B and C (1 and 2), and one known diterpenoid, were isolated from the aerial parts of Clerodendranthus spicatus. Their structures including absolute configurations were determined by comprehensive spectroscopic analyses and X-ray crystallographic methods. No c...

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Detalles Bibliográficos
Autores principales: Li, Ya-Mei, Xiang, Bing, Li, Xiao-Zheng, Yan, Yong-Ming, Cheng, Yong-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481273/
https://www.ncbi.nlm.nih.gov/pubmed/28470482
http://dx.doi.org/10.1007/s13659-017-0128-8
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author Li, Ya-Mei
Xiang, Bing
Li, Xiao-Zheng
Yan, Yong-Ming
Cheng, Yong-Xian
author_facet Li, Ya-Mei
Xiang, Bing
Li, Xiao-Zheng
Yan, Yong-Ming
Cheng, Yong-Xian
author_sort Li, Ya-Mei
collection PubMed
description Two new diterpenoids, neoorthosiphonones B and C (1 and 2), and one known diterpenoid, were isolated from the aerial parts of Clerodendranthus spicatus. Their structures including absolute configurations were determined by comprehensive spectroscopic analyses and X-ray crystallographic methods. No compound was found to inhibit fibronectin production at the concentration of 20 μM. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13659-017-0128-8) contains supplementary material, which is available to authorized users.
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spelling pubmed-54812732017-07-07 New Diterpenoids from Clerodendranthus spicatus Li, Ya-Mei Xiang, Bing Li, Xiao-Zheng Yan, Yong-Ming Cheng, Yong-Xian Nat Prod Bioprospect Original Article Two new diterpenoids, neoorthosiphonones B and C (1 and 2), and one known diterpenoid, were isolated from the aerial parts of Clerodendranthus spicatus. Their structures including absolute configurations were determined by comprehensive spectroscopic analyses and X-ray crystallographic methods. No compound was found to inhibit fibronectin production at the concentration of 20 μM. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13659-017-0128-8) contains supplementary material, which is available to authorized users. Springer Singapore 2017-05-03 /pmc/articles/PMC5481273/ /pubmed/28470482 http://dx.doi.org/10.1007/s13659-017-0128-8 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Li, Ya-Mei
Xiang, Bing
Li, Xiao-Zheng
Yan, Yong-Ming
Cheng, Yong-Xian
New Diterpenoids from Clerodendranthus spicatus
title New Diterpenoids from Clerodendranthus spicatus
title_full New Diterpenoids from Clerodendranthus spicatus
title_fullStr New Diterpenoids from Clerodendranthus spicatus
title_full_unstemmed New Diterpenoids from Clerodendranthus spicatus
title_short New Diterpenoids from Clerodendranthus spicatus
title_sort new diterpenoids from clerodendranthus spicatus
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481273/
https://www.ncbi.nlm.nih.gov/pubmed/28470482
http://dx.doi.org/10.1007/s13659-017-0128-8
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AT yanyongming newditerpenoidsfromclerodendranthusspicatus
AT chengyongxian newditerpenoidsfromclerodendranthusspicatus

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