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Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells

Adaptation to hypoxia, a hallmark feature of many tumors, is an important driver of cancer cell survival, proliferation and the development of resistance to chemotherapy. Hypoxia-induced stabilization of hypoxia-inducible factors (HIFs) leads to transcriptional activation of a network of hypoxia tar...

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Detalles Bibliográficos
Autores principales:	Han, Jian, Li, Jia, Ho, Jolene Caifeng, Chia, Grace Sushin, Kato, Hiroyuki, Jha, Sudhakar, Yang, Henry, Poellinger, Lorenz, Lee, Kian Leong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481333/ https://www.ncbi.nlm.nih.gov/pubmed/28642487 http://dx.doi.org/10.1038/s41598-017-04333-0

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