Sphingosine-1-Phosphate Treatment Can Ameliorate Microvascular Leakage Caused by Combined Alcohol Intoxication and Hemorrhagic Shock

Fluid resuscitation following hemorrhagic shock is often problematic, with development of prolonged hypotension and edema. In addition, many trauma patients are also intoxicated, which generally worsens outcomes. We directly investigated how alcohol intoxication impacts hemorrhagic shock and resusci...

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Detalles Bibliográficos
Autores principales: Doggett, Travis M., Alves, Natascha G., Yuan, Sarah Y., Breslin, Jerome W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481382/
https://www.ncbi.nlm.nih.gov/pubmed/28642485
http://dx.doi.org/10.1038/s41598-017-04157-y

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