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Inhibition of TNFalpha in vivo prevents hyperoxia-mediated activation of caspase 3 in type II cells

BACKGROUND: The mechanisms during the initial phase of oxygen toxicity leading to pulmonary tissue damage are incompletely known. Increase of tumour necrosis factor alpha (TNFalpha) represents one of the first pulmonary responses to hyperoxia. We hypothesised that, in the initial phase of hyperoxia,...

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Detalles Bibliográficos
Autores principales: Guthmann, Florian, Wissel, Heide, Schachtrup, Christian, Tölle, Angelika, Rüdiger, Mario, Spener, Friedrich, Rüstow, Bernd
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548140/
https://www.ncbi.nlm.nih.gov/pubmed/15663790
http://dx.doi.org/10.1186/1465-9921-6-10

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