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Inhibition of TNFalpha in vivo prevents hyperoxia-mediated activation of caspase 3 in type II cells
BACKGROUND: The mechanisms during the initial phase of oxygen toxicity leading to pulmonary tissue damage are incompletely known. Increase of tumour necrosis factor alpha (TNFalpha) represents one of the first pulmonary responses to hyperoxia. We hypothesised that, in the initial phase of hyperoxia,...
Autores principales: | Guthmann, Florian, Wissel, Heide, Schachtrup, Christian, Tölle, Angelika, Rüdiger, Mario, Spener, Friedrich, Rüstow, Bernd |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548140/ https://www.ncbi.nlm.nih.gov/pubmed/15663790 http://dx.doi.org/10.1186/1465-9921-6-10 |
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