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Oncogenic Activity of Amplified Miniature Chromosome Maintenance 8 in Human Malignancies

Miniature chromosome maintenance (MCM) proteins play critical roles in DNA replication licensing, initiation and elongation. MCM8, one of the MCM proteins playing a critical role in DNA repairing and recombination, was found to have over-expression and increased DNA copy number in a variety of human...

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Detalles Bibliográficos
Autores principales: He, Dong-Mei, Ren, Bao-Guo, Liu, Silvia, Tang, Lang-Zhu, Cieply, Kathleen, Tseng, George, Yu, Yan P., Luo, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481462/
https://www.ncbi.nlm.nih.gov/pubmed/28481876
http://dx.doi.org/10.1038/onc.2017.123