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Oncogenic Activity of Amplified Miniature Chromosome Maintenance 8 in Human Malignancies
Miniature chromosome maintenance (MCM) proteins play critical roles in DNA replication licensing, initiation and elongation. MCM8, one of the MCM proteins playing a critical role in DNA repairing and recombination, was found to have over-expression and increased DNA copy number in a variety of human...
Autores principales: | He, Dong-Mei, Ren, Bao-Guo, Liu, Silvia, Tang, Lang-Zhu, Cieply, Kathleen, Tseng, George, Yu, Yan P., Luo, Jian-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481462/ https://www.ncbi.nlm.nih.gov/pubmed/28481876 http://dx.doi.org/10.1038/onc.2017.123 |
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