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Importance of producing economic compounds to combat cancer

The manuscript published by Microb Biotechnol, volume 10, highlights the relevance of the fungus Nigrospora sphaerica, an endophyte isolated from Catharanthus roseus, as an alternative source to obtain vinblastine, a compound used in chemotherapy schemes to treat several types of cancer. Authors sho...

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Detalles Bibliográficos
Autor principal: Muñoz‐Rojas, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481543/
https://www.ncbi.nlm.nih.gov/pubmed/28127869
http://dx.doi.org/10.1111/1751-7915.12491
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author Muñoz‐Rojas, Jesús
author_facet Muñoz‐Rojas, Jesús
author_sort Muñoz‐Rojas, Jesús
collection PubMed
description The manuscript published by Microb Biotechnol, volume 10, highlights the relevance of the fungus Nigrospora sphaerica, an endophyte isolated from Catharanthus roseus, as an alternative source to obtain vinblastine, a compound used in chemotherapy schemes to treat several types of cancer. Authors showed that purification of vinblastine from extracts of the fungus has higher activity and yield in comparison with that obtained from the plant Catharanthus roseus. This work represents a biotechnological approach to obtain vinblastine with promising results to decrease the production cost.
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spelling pubmed-54815432017-06-23 Importance of producing economic compounds to combat cancer Muñoz‐Rojas, Jesús Microb Biotechnol Highlight The manuscript published by Microb Biotechnol, volume 10, highlights the relevance of the fungus Nigrospora sphaerica, an endophyte isolated from Catharanthus roseus, as an alternative source to obtain vinblastine, a compound used in chemotherapy schemes to treat several types of cancer. Authors showed that purification of vinblastine from extracts of the fungus has higher activity and yield in comparison with that obtained from the plant Catharanthus roseus. This work represents a biotechnological approach to obtain vinblastine with promising results to decrease the production cost. John Wiley and Sons Inc. 2017-01-26 /pmc/articles/PMC5481543/ /pubmed/28127869 http://dx.doi.org/10.1111/1751-7915.12491 Text en © 2017 The Author. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Highlight
Muñoz‐Rojas, Jesús
Importance of producing economic compounds to combat cancer
title Importance of producing economic compounds to combat cancer
title_full Importance of producing economic compounds to combat cancer
title_fullStr Importance of producing economic compounds to combat cancer
title_full_unstemmed Importance of producing economic compounds to combat cancer
title_short Importance of producing economic compounds to combat cancer
title_sort importance of producing economic compounds to combat cancer
topic Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481543/
https://www.ncbi.nlm.nih.gov/pubmed/28127869
http://dx.doi.org/10.1111/1751-7915.12491
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