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Importance of producing economic compounds to combat cancer
The manuscript published by Microb Biotechnol, volume 10, highlights the relevance of the fungus Nigrospora sphaerica, an endophyte isolated from Catharanthus roseus, as an alternative source to obtain vinblastine, a compound used in chemotherapy schemes to treat several types of cancer. Authors sho...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley and Sons Inc.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481543/ https://www.ncbi.nlm.nih.gov/pubmed/28127869 http://dx.doi.org/10.1111/1751-7915.12491 |
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author | Muñoz‐Rojas, Jesús |
author_facet | Muñoz‐Rojas, Jesús |
author_sort | Muñoz‐Rojas, Jesús |
collection | PubMed |
description | The manuscript published by Microb Biotechnol, volume 10, highlights the relevance of the fungus Nigrospora sphaerica, an endophyte isolated from Catharanthus roseus, as an alternative source to obtain vinblastine, a compound used in chemotherapy schemes to treat several types of cancer. Authors showed that purification of vinblastine from extracts of the fungus has higher activity and yield in comparison with that obtained from the plant Catharanthus roseus. This work represents a biotechnological approach to obtain vinblastine with promising results to decrease the production cost. |
format | Online Article Text |
id | pubmed-5481543 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-54815432017-06-23 Importance of producing economic compounds to combat cancer Muñoz‐Rojas, Jesús Microb Biotechnol Highlight The manuscript published by Microb Biotechnol, volume 10, highlights the relevance of the fungus Nigrospora sphaerica, an endophyte isolated from Catharanthus roseus, as an alternative source to obtain vinblastine, a compound used in chemotherapy schemes to treat several types of cancer. Authors showed that purification of vinblastine from extracts of the fungus has higher activity and yield in comparison with that obtained from the plant Catharanthus roseus. This work represents a biotechnological approach to obtain vinblastine with promising results to decrease the production cost. John Wiley and Sons Inc. 2017-01-26 /pmc/articles/PMC5481543/ /pubmed/28127869 http://dx.doi.org/10.1111/1751-7915.12491 Text en © 2017 The Author. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Highlight Muñoz‐Rojas, Jesús Importance of producing economic compounds to combat cancer |
title | Importance of producing economic compounds to combat cancer |
title_full | Importance of producing economic compounds to combat cancer |
title_fullStr | Importance of producing economic compounds to combat cancer |
title_full_unstemmed | Importance of producing economic compounds to combat cancer |
title_short | Importance of producing economic compounds to combat cancer |
title_sort | importance of producing economic compounds to combat cancer |
topic | Highlight |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481543/ https://www.ncbi.nlm.nih.gov/pubmed/28127869 http://dx.doi.org/10.1111/1751-7915.12491 |
work_keys_str_mv | AT munozrojasjesus importanceofproducingeconomiccompoundstocombatcancer |