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Genetic metabolic complementation establishes a requirement for GDP-fucose in Leishmania

To survive in its sand fly vector, the trypanosomatid protozoan parasite Leishmania first attaches to the midgut to avoid excretion, but eventually it must detach for transmission by the next bite. In Leishmania major strain Friedlin, this is controlled by modifications of the stage-specific adhesin...

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Detalles Bibliográficos
Autores principales: Guo, Hongjie, Novozhilova, Natalia M., Bandini, Giulia, Turco, Salvatore J., Ferguson, Michael A. J., Beverley, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481574/
https://www.ncbi.nlm.nih.gov/pubmed/28465349
http://dx.doi.org/10.1074/jbc.M117.778480

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