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Inhibition of casein kinase 2 blocks G(2)/M transition in early embryo mitosis but not in oocyte meiosis in mouse

Casein kinase 2 (CK2) is a highly conserved, ubiquitously expressed serine/threonine protein kinase with hundreds of substrates. The role of CK2 in the G(2)/M transition of oocytes, zygotes, and 2-cell embryos was studied in mouse by enzyme activity inhibition using the specific inhibitor 4, 5, 6, 7...

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Detalles Bibliográficos
Autores principales: LIN, Fei, CAO, Shi-Bing, MA, Xue-Shan, SUN, Hai-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481635/
https://www.ncbi.nlm.nih.gov/pubmed/28367932
http://dx.doi.org/10.1262/jrd.2016-064