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Inhibition of casein kinase 2 blocks G(2)/M transition in early embryo mitosis but not in oocyte meiosis in mouse
Casein kinase 2 (CK2) is a highly conserved, ubiquitously expressed serine/threonine protein kinase with hundreds of substrates. The role of CK2 in the G(2)/M transition of oocytes, zygotes, and 2-cell embryos was studied in mouse by enzyme activity inhibition using the specific inhibitor 4, 5, 6, 7...
Autores principales: | LIN, Fei, CAO, Shi-Bing, MA, Xue-Shan, SUN, Hai-Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Society for Reproduction and Development
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481635/ https://www.ncbi.nlm.nih.gov/pubmed/28367932 http://dx.doi.org/10.1262/jrd.2016-064 |
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