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Stapled Voltage-Gated Calcium Channel (Ca(V)) α-Interaction Domain (AID) Peptides Act As Selective Protein–Protein Interaction Inhibitors of Ca(V) Function
[Image: see text] For many voltage-gated ion channels (VGICs), creation of a properly functioning ion channel requires the formation of specific protein–protein interactions between the transmembrane pore-forming subunits and cystoplasmic accessory subunits. Despite the importance of such protein–pr...
Autores principales: | Findeisen, Felix, Campiglio, Marta, Jo, Hyunil, Abderemane-Ali, Fayal, Rumpf, Christine H., Pope, Lianne, Rossen, Nathan D., Flucher, Bernhard E., DeGrado, William F., Minor, Daniel L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2017
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481814/ https://www.ncbi.nlm.nih.gov/pubmed/28278376 http://dx.doi.org/10.1021/acschemneuro.6b00454 |
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