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Construction of a synthetic metabolic pathway for biosynthesis of the non-natural methionine precursor 2,4-dihydroxybutyric acid
2,4-Dihydroxybutyric acid (DHB) is a molecule with considerable potential as a versatile chemical synthon. Notably, it may serve as a precursor for chemical synthesis of the methionine analogue 2-hydroxy-4-(methylthio)butyrate, thus, targeting a considerable market in animal nutrition. However, no n...
Autores principales: | Walther, Thomas, Topham, Christopher M., Irague, Romain, Auriol, Clément, Baylac, Audrey, Cordier, Hélène, Dressaire, Clémentine, Lozano-Huguet, Luce, Tarrat, Nathalie, Martineau, Nelly, Stodel, Marion, Malbert, Yannick, Maestracci, Marc, Huet, Robert, André, Isabelle, Remaud-Siméon, Magali, François, Jean Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481828/ https://www.ncbi.nlm.nih.gov/pubmed/28631755 http://dx.doi.org/10.1038/ncomms15828 |
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