Identification of the flotillin-1/2 heterocomplex as a target of autoantibodies in bona fide multiple sclerosis

BACKGROUND: Autoantibodies, in particular those against aquaporin-4 and myelin-oligodendrocyte glycoprotein (MOG), aid as biomarkers in the differential diagnosis of demyelination. Here, we report on discovery of autoantibodies against flotillin in patients with multiple sclerosis (MS). METHODS: The...

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Detalles Bibliográficos
Autores principales: Hahn, S., Trendelenburg, G., Scharf, M., Denno, Y., Brakopp, S., Teegen, B., Probst, C., Wandinger, K. P., Buttmann, M., Haarmann, A., Szabados, F., vom Dahl, M., Kümpfel, T., Eichhorn, P., Gold, H., Paul, F., Jarius, S., Melzer, N., Stöcker, W., Komorowski, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481867/
https://www.ncbi.nlm.nih.gov/pubmed/28645295
http://dx.doi.org/10.1186/s12974-017-0900-z

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