Sac-1004, a vascular leakage blocker, reduces cerebral ischemia—reperfusion injury by suppressing blood–brain barrier disruption and inflammation

BACKGROUND: Blood–brain barrier (BBB) breakdown and inflammation are critical events in ischemic stroke, contributing to aggravated brain damage. The BBB mainly consists of microvascular endothelial cells sealed by tight junctions to protect the brain from blood-borne substances. Thus, the maintenan...

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Detalles Bibliográficos
Autores principales: Zhang, Haiying, Park, Joon Ha, Maharjan, Sony, Park, Jeong Ae, Choi, Kyu-Sung, Park, Hyojin, Jeong, Yoonjeong, Ahn, Ji Hyeon, Kim, In Hye, Lee, Jae-Chul, Cho, Jeong Hwi, Lee, In-Kyu, Lee, Choong Hyun, Hwang, In Koo, Kim, Young-Myeong, Suh, Young-Ger, Won, Moo-Ho, Kwon, Young-Guen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481915/
https://www.ncbi.nlm.nih.gov/pubmed/28645333
http://dx.doi.org/10.1186/s12974-017-0897-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481915/
https://www.ncbi.nlm.nih.gov/pubmed/28645333
http://dx.doi.org/10.1186/s12974-017-0897-3

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