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Establishment of an orthotopic patient-derived xenograft mouse model using uveal melanoma hepatic metastasis
BACKGROUND: Metastatic uveal melanoma is a highly fatal disease; most patients die from their hepatic metastasis within 1 year. A major drawback in the development of new treatments for metastatic uveal melanoma is the difficulty in obtaining appropriate cell lines and the lack of appropriate animal...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481921/ https://www.ncbi.nlm.nih.gov/pubmed/28645290 http://dx.doi.org/10.1186/s12967-017-1247-z |