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MyD88-dependent pro-interleukin-1β induction in dendritic cells exposed to food-grade synthetic amorphous silica
BACKGROUND: Dendritic cells (DCs) are specialized first-line sensors of foreign materials invading the organism. These sentinel cells rely on pattern recognition receptors such as Nod-like or Toll-like receptors (TLRs) to launch immune reactions against pathogens, but also to mediate tolerance to se...
Autores principales: | Winkler, Hans Christian, Kornprobst, Julian, Wick, Peter, von Moos, Lea Maria, Trantakis, Ioannis, Schraner, Elisabeth Maria, Bathke, Barbara, Hochrein, Hubertus, Suter, Mark, Naegeli, Hanspeter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481969/ https://www.ncbi.nlm.nih.gov/pubmed/28645296 http://dx.doi.org/10.1186/s12989-017-0202-8 |
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