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Growth of organic crystals via attachment and transformation of nanoscopic precursors

A key requirement for the understanding of crystal growth is to detect how new layers form and grow at the nanoscale. Multistage crystallization pathways involving liquid-like, amorphous or metastable crystalline precursors have been predicted by theoretical work and have been observed experimentall...

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Autores principales: Jiang, Yuan, Kellermeier, Matthias, Gebauer, Denis, Lu, Zihao, Rosenberg, Rose, Moise, Adrian, Przybylski, Michael, Cölfen, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482053/
https://www.ncbi.nlm.nih.gov/pubmed/28635962
http://dx.doi.org/10.1038/ncomms15933
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author Jiang, Yuan
Kellermeier, Matthias
Gebauer, Denis
Lu, Zihao
Rosenberg, Rose
Moise, Adrian
Przybylski, Michael
Cölfen, Helmut
author_facet Jiang, Yuan
Kellermeier, Matthias
Gebauer, Denis
Lu, Zihao
Rosenberg, Rose
Moise, Adrian
Przybylski, Michael
Cölfen, Helmut
author_sort Jiang, Yuan
collection PubMed
description A key requirement for the understanding of crystal growth is to detect how new layers form and grow at the nanoscale. Multistage crystallization pathways involving liquid-like, amorphous or metastable crystalline precursors have been predicted by theoretical work and have been observed experimentally. Nevertheless, there is no clear evidence that any of these precursors can also be relevant for the growth of crystals of organic compounds. Herein, we present a new growth mode for crystals of DL-glutamic acid monohydrate that proceeds through the attachment of preformed nanoscopic species from solution, their subsequent decrease in height at the surface and final transformation into crystalline 2D nuclei that eventually build new molecular layers by further monomer incorporation. This alternative mechanism provides a direct proof for the existence of multistage pathways in the crystallization of molecular compounds and the relevance of precursor units larger than the monomeric constituents in the actual stage of growth.
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spelling pubmed-54820532017-07-06 Growth of organic crystals via attachment and transformation of nanoscopic precursors Jiang, Yuan Kellermeier, Matthias Gebauer, Denis Lu, Zihao Rosenberg, Rose Moise, Adrian Przybylski, Michael Cölfen, Helmut Nat Commun Article A key requirement for the understanding of crystal growth is to detect how new layers form and grow at the nanoscale. Multistage crystallization pathways involving liquid-like, amorphous or metastable crystalline precursors have been predicted by theoretical work and have been observed experimentally. Nevertheless, there is no clear evidence that any of these precursors can also be relevant for the growth of crystals of organic compounds. Herein, we present a new growth mode for crystals of DL-glutamic acid monohydrate that proceeds through the attachment of preformed nanoscopic species from solution, their subsequent decrease in height at the surface and final transformation into crystalline 2D nuclei that eventually build new molecular layers by further monomer incorporation. This alternative mechanism provides a direct proof for the existence of multistage pathways in the crystallization of molecular compounds and the relevance of precursor units larger than the monomeric constituents in the actual stage of growth. Nature Publishing Group 2017-06-21 /pmc/articles/PMC5482053/ /pubmed/28635962 http://dx.doi.org/10.1038/ncomms15933 Text en Copyright © 2017, The Author(s) http://creativecommons.org/licenses/by/4.0/ Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Jiang, Yuan
Kellermeier, Matthias
Gebauer, Denis
Lu, Zihao
Rosenberg, Rose
Moise, Adrian
Przybylski, Michael
Cölfen, Helmut
Growth of organic crystals via attachment and transformation of nanoscopic precursors
title Growth of organic crystals via attachment and transformation of nanoscopic precursors
title_full Growth of organic crystals via attachment and transformation of nanoscopic precursors
title_fullStr Growth of organic crystals via attachment and transformation of nanoscopic precursors
title_full_unstemmed Growth of organic crystals via attachment and transformation of nanoscopic precursors
title_short Growth of organic crystals via attachment and transformation of nanoscopic precursors
title_sort growth of organic crystals via attachment and transformation of nanoscopic precursors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482053/
https://www.ncbi.nlm.nih.gov/pubmed/28635962
http://dx.doi.org/10.1038/ncomms15933
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