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σ-1 receptor stimulation protects against pressure-induced damage through InsR-MAPK signaling in human trabecular meshwork cells

The purpose of the present study was to investigate the protective effect of the σ-1 receptor (Sig-1R) agonist (+)-pentazocin (PTZ) on pressure-induced apoptosis and death of human trabecular meshwork cells (hTMCs). The expression levels of Sig-1R and insulin receptor (InsR) were examined in hTMCs....

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Detalles Bibliográficos
Autores principales:	Meng, Bo, Li, Hongyi, Sun, Xian, Qu, Wei, Yang, Binbin, Cheng, Fang, Shi, Liping, Yuan, Huiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482118/ https://www.ncbi.nlm.nih.gov/pubmed/28560459 http://dx.doi.org/10.3892/mmr.2017.6647

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