Upregulation of SOCS3 in lung CD4(+) T cells in a mouse model of chronic PA lung infection and suppression of Th17-mediated neutrophil recruitment in exogenous SOCS3 transfer in vitro

Neutrophilic airway inflammation in chronic lung infections caused by Pseudomonas aeruginosa (PA) is associated with T helper (Th)17 responses. Suppressor of cytokine signaling 3 (SOCS3) is the major negative modulator of Th17 function through the suppression of signal transducer and activator of tr...

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Detalles Bibliográficos
Autores principales: Ding, Feng-Ming, Liao, Ruo-Min, Chen, Yu-Qing, Xie, Guo-Gang, Zhang, Peng-Yu, Shao, Ping, Zhang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482193/
https://www.ncbi.nlm.nih.gov/pubmed/28560450
http://dx.doi.org/10.3892/mmr.2017.6630

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