Cargando…

Elemene inhibits the migration and invasion of 4T1 murine breast cancer cells via heparanase

Elemene (ELE), a natural plant drug extracted from Curcumae Rhizoma, has been widely used for cancer treatment in China for more than 20 years. Although it is reported to be a broad-spectrum anticancer drug, the mechanism underlying the action of ELE in the treatment of breast cancer remains to be f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yi, Sun, Xu, Nan, Nan, Cao, Ke-Xin, Ma, Cong, Yang, Guo-Wang, Yu, Ming-Wei, Yang, Lin, Li, Jin-Ping, Wang, Xiao-Min, Zhang, Gan-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482194/ https://www.ncbi.nlm.nih.gov/pubmed/28560389 http://dx.doi.org/10.3892/mmr.2017.6638

Ejemplares similares

Gubenyiliu II Inhibits Breast Tumor Growth and Metastasis Associated with Decreased Heparanase Expression and Phosphorylation of ERK and AKT Pathways
por: Zhang, Yi, et al.
Publicado: (2017)

Heparanase from triple-negative breast cancer and platelets acts as an enhancer of metastasis
por: Yang, Wen-Jing, et al.
Publicado: (2020)

Combinative effects of β-elemene and propranolol on the proliferation, migration, and angiogenesis of hemangioma
por: Wang, Zhenyu, et al.
Publicado: (2023)

Gene silencing of heparanase results in suppression of invasion and migration of hepatoma cells
por: Dong, Weiwei, et al.
Publicado: (2014)

MicroRNA-429 decreases the invasion ability of gastric cancer cell line BGC-823 by downregulating the expression of heparanase
por: Sheng, Nan, et al.
Publicado: (2018)

Establishment of a murine breast tumor model by subcutaneous or orthotopic implantation
por: Zhang, Yi, et al.
Publicado: (2018)

β-elemene inhibits non-small cell lung cancer cell migration and invasion by inactivating the FAK-Src pathway
por: Zhang, Hongbo, et al.
Publicado: (2021)

Downregulation of Heparanase Expression Results in Suppression of Invasion, Migration, and Adhesion Abilities of Hepatocellular Carcinoma Cells
por: Chen, Xiao-Peng, et al.
Publicado: (2015)

Inhibition of Heparanase Expression Results in Suppression of Invasion, Migration and Adhesion Abilities of Bladder Cancer Cells
por: Tatsumi, Yoshihiro, et al.
Publicado: (2020)

β‐Elemene Selectively Inhibits the Proliferation of Glioma Stem‐Like Cells Through the Downregulation of Notch1
por: Feng, Hai‐bin, et al.
Publicado: (2016)

β-Elemene Inhibits the Proliferation and Migration of Human Glioblastoma Cell Lines via Suppressing Ring Finger Protein 135
por: Alizada, M, et al.
Publicado: (2020)

Downregulation of heparanase by RNA interference inhibits invasion and tumorigenesis of hepatocellular cancer cells in vitro and in vivo
por: Xiong, Zhen, et al.
Publicado: (2022)

The reversal of antineoplastic drug resistance in cancer cells by β-elemene
por: Zhang, Guan-Nan, et al.
Publicado: (2015)

Suppression of endoplasmic reticulum stress-induced invasion and migration of breast cancer cells through the downregulation of heparanase
por: Li, Yang, et al.
Publicado: (2021)

Heparanase potentiates the invasion and migration of pancreatic cancer cells via epithelial-to-mesenchymal transition through the Wnt/β-catenin pathway
por: Wang, Cheng, et al.
Publicado: (2020)

β-Elemene inhibits the proliferation of primary human airway granulation fibroblasts by down-regulating canonical Wnt/β-catenin pathway
por: Xue, Cheng, et al.
Publicado: (2018)

β-Elemene Promotes Apoptosis Induced by Hyperthermia via Inhibiting HSP70
por: Zhang, Cuiwei, et al.
Publicado: (2022)

Role of heparanase in pulmonary hypertension
por: Wang, Lin-Jun, et al.
Publicado: (2023)

Elémens de Chimie
Publicado: (1836)

Antitumor effects of β-elemene via targeting the phosphorylation of insulin receptor
por: Wu, Dawei, et al.
Publicado: (2018)

Beta-elemene inhibits differentiated thyroid carcinoma metastasis by reducing cellular proliferation, metabolism and invasion ability
por: Zhao, Lei, et al.
Publicado: (2020)

Elemene Nanoemulsion Inhibits Metastasis of Breast Cancer by ROS Scavenging
por: Han, Bo, et al.
Publicado: (2021)

Drug delivery systems for elemene, its main active ingredient β-elemene, and its derivatives in cancer therapy
por: Zhai, Bingtao, et al.
Publicado: (2018)

The analgesic effects of β-elemene in rats with neuropathic pain by inhibition of spinal astrocytic ERK activation
por: Ma, Li-Tian, et al.
Publicado: (2022)

Heparanase Contributes To Trans-Endothelial Migration of Hepatocellular Carcinoma Cells
por: Chen, Xiaopeng, et al.
Publicado: (2017)

Suramin inhibits cell proliferation in ovarian and cervical cancer by downregulating heparanase expression
por: Li, HuaPing, et al.
Publicado: (2015)

Radiation-Induced Nephropathy in the Murine Model Is Ameliorated by Targeting Heparanase
por: Abecassis, Alexia, et al.
Publicado: (2023)

Élemens de pathologie chirurgicale

Knockdown of Heparanase Suppresses Invasion of Human Trophoblasts by Activating p38 MAPK Signaling Pathway
por: Che, Guanglu, et al.
Publicado: (2018)

β-elemene combined with temozolomide in treatment of brain glioma
por: Zhang, Xiaomin, et al.
Publicado: (2021)

Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain
por: Zhang, Xiao, et al.
Publicado: (2012)

Heparanase overexpression impedes perivascular clearance of amyloid-β from murine brain: relevance to Alzheimer’s disease
por: Zhang, Xiao, et al.
Publicado: (2021)

β-Elemene Inhibits Cell Proliferation by Regulating the Expression and Activity of Topoisomerases I and IIα in Human Hepatocarcinoma HepG-2 Cells
por: Gong, Min, et al.
Publicado: (2015)

Hyperoside pre-treatment prevents glomerular basement membrane damage in diabetic nephropathy by inhibiting podocyte heparanase expression
por: An, Xiaofei, et al.
Publicado: (2017)

Treatment with β-elemene combined with paclitaxel inhibits growth, migration, and invasion and induces apoptosis of ovarian cancer cells by activation of STAT-NF-κB pathway
por: Xiaomeng, Fu, et al.
Publicado: (2020)

SYL3C aptamer-anchored microemulsion co-loading β-elemene and PTX enhances the treatment of colorectal cancer
por: Zhou, Xiaorong, et al.
Publicado: (2019)

Newly Generated Heparanase Knock-Out Mice Unravel Co-Regulation of Heparanase and Matrix Metalloproteinases
por: Zcharia, Eyal, et al.
Publicado: (2009)

MicroRNA-1258: An invasion and metastasis regulator that targets heparanase in gastric cancer
por: Shi, Jinxin, et al.
Publicado: (2021)

Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells
por: Cheng, Chun-Chun, et al.
Publicado: (2014)

Heparanase is a novel biomarker for immune infiltration and prognosis in breast cancer
por: Yang, Wen-Jing, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jbi5i18btmo4p2u8p1ns0fmkts