Large-field-of-view imaging by Multi-Pupil Adaptive Optics

For in vivo deep imaging at high spatiotemporal resolutions, we developed Multi-Pupil Adaptive Optics (MPAO) which enables simultaneous wavefront correction over a large imaging field-of-view. The current implementation improves correction area by nine times over that of conventional methods. MPAO’s...

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Detalles Bibliográficos
Autores principales: Park, Jung-Hoon, Kong, Lingjie, Zhou, Yifeng, Cui, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482233/
https://www.ncbi.nlm.nih.gov/pubmed/28481364
http://dx.doi.org/10.1038/nmeth.4290
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author Park, Jung-Hoon
Kong, Lingjie
Zhou, Yifeng
Cui, Meng
author_facet Park, Jung-Hoon
Kong, Lingjie
Zhou, Yifeng
Cui, Meng
author_sort Park, Jung-Hoon
collection PubMed
description For in vivo deep imaging at high spatiotemporal resolutions, we developed Multi-Pupil Adaptive Optics (MPAO) which enables simultaneous wavefront correction over a large imaging field-of-view. The current implementation improves correction area by nine times over that of conventional methods. MPAO’s capability of spatially independent wavefront control further enables 3D nonplanar imaging. We applied MPAO to in vivo structural and functional imaging of biological dynamics in mammalian brain.
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spelling pubmed-54822332017-11-08 Large-field-of-view imaging by Multi-Pupil Adaptive Optics Park, Jung-Hoon Kong, Lingjie Zhou, Yifeng Cui, Meng Nat Methods Article For in vivo deep imaging at high spatiotemporal resolutions, we developed Multi-Pupil Adaptive Optics (MPAO) which enables simultaneous wavefront correction over a large imaging field-of-view. The current implementation improves correction area by nine times over that of conventional methods. MPAO’s capability of spatially independent wavefront control further enables 3D nonplanar imaging. We applied MPAO to in vivo structural and functional imaging of biological dynamics in mammalian brain. 2017-05-08 2017-06 /pmc/articles/PMC5482233/ /pubmed/28481364 http://dx.doi.org/10.1038/nmeth.4290 Text en Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Park, Jung-Hoon
Kong, Lingjie
Zhou, Yifeng
Cui, Meng
Large-field-of-view imaging by Multi-Pupil Adaptive Optics
title Large-field-of-view imaging by Multi-Pupil Adaptive Optics
title_full Large-field-of-view imaging by Multi-Pupil Adaptive Optics
title_fullStr Large-field-of-view imaging by Multi-Pupil Adaptive Optics
title_full_unstemmed Large-field-of-view imaging by Multi-Pupil Adaptive Optics
title_short Large-field-of-view imaging by Multi-Pupil Adaptive Optics
title_sort large-field-of-view imaging by multi-pupil adaptive optics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482233/
https://www.ncbi.nlm.nih.gov/pubmed/28481364
http://dx.doi.org/10.1038/nmeth.4290
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AT zhouyifeng largefieldofviewimagingbymultipupiladaptiveoptics
AT cuimeng largefieldofviewimagingbymultipupiladaptiveoptics

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