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Investigation of discriminant metabolites in tamoxifen-resistant and choline kinase-alpha-downregulated breast cancer cells using (1)H-nuclear magnetic resonance spectroscopy

Metabolites linked to changes in choline kinase-α (CK-α) expression and drug resistance, which contribute to survival and autophagy mechanisms, are attractive targets for breast cancer therapies. We previously reported that autophagy played a causative role in driving tamoxifen (TAM) resistance of b...

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Detalles Bibliográficos
Autores principales:	Kim, Hoe Suk, Tian, Lianji, Kim, Hyeonjin, Moon, Woo Kyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482454/ https://www.ncbi.nlm.nih.gov/pubmed/28644842 http://dx.doi.org/10.1371/journal.pone.0179773

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