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Organic anion transporting polypeptide 1B3 can form homo- and hetero-oligomers

OATP1B3 is a 12 transmembrane domain protein expressed at the basolateral membrane of human hepatocytes where it mediates the uptake of numerous drugs and endogenous compounds. Previous western blot results suggest the formation of OATP1B3 multimers. In order to better understand the function of OAT...

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Detalles Bibliográficos
Autores principales: Zhang, Yuchen, Boxberger, Kelli H., Hagenbuch, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482489/
https://www.ncbi.nlm.nih.gov/pubmed/28644885
http://dx.doi.org/10.1371/journal.pone.0180257