Cargando…

Organic anion transporting polypeptide 1B3 can form homo- and hetero-oligomers

OATP1B3 is a 12 transmembrane domain protein expressed at the basolateral membrane of human hepatocytes where it mediates the uptake of numerous drugs and endogenous compounds. Previous western blot results suggest the formation of OATP1B3 multimers. In order to better understand the function of OAT...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yuchen, Boxberger, Kelli H., Hagenbuch, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482489/ https://www.ncbi.nlm.nih.gov/pubmed/28644885 http://dx.doi.org/10.1371/journal.pone.0180257

Ejemplares similares

Cysteine Scanning Mutagenesis of Transmembrane Domain 10 in Organic Anion Transporting Polypeptide 1B1
por: Ohnishi, Shuichi, et al.
Publicado: (2014)

Two Arabidopsis Chloroplast GrpE Homologues Exhibit Distinct Biological Activities and Can Form Homo- and Hetero-Oligomers
por: Su, Pai-Hsiang, et al.
Publicado: (2020)

Development of a Cell-Based High-Throughput Assay to Screen for Inhibitors of Organic Anion Transporting Polypeptides 1B1 and 1B3
por: Gui, Chunshan, et al.
Publicado: (2010)

Modeling protein quaternary structure of homo- and hetero-oligomers beyond binary interactions by homology
por: Bertoni, Martino, et al.
Publicado: (2017)

Overview of organic anion transporters and organic anion transporter polypeptides and their roles in the liver
por: Li, Ting-Ting, et al.
Publicado: (2019)

Organic anion transporter 3- and organic anion transporting polypeptides 1B1- and 1B3-mediated transport of catalposide
por: Jeong, Hyeon-Uk, et al.
Publicado: (2015)

AKAP5 and AKAP12 Form Homo-oligomers
por: Gao, Shujuan, et al.
Publicado: (2011)

Stimulatory effect on the transport mediated by organic anion transporting polypeptide 2B1
por: Ogura, Jiro, et al.
Publicado: (2020)

Free Cholesterol Affects the Function and Localization of Human Na(+)/Taurocholate Cotransporting Polypeptide (NTCP) and Organic Cation Transporter 1 (OCT1)
por: Idowu, Jessica Y., et al.
Publicado: (2022)

AKAP12 and AKAP5 form higher-order hetero-oligomers
por: Gao, Shujuan, et al.
Publicado: (2011)

Establishment of an experimental model for MHC homo-to-hetero transplantation
por: Murata, Tomoki, et al.
Publicado: (2020)

N-glycosylation Dictates Proper Processing of Organic Anion Transporting Polypeptide 1B1
por: Yao, Juan, et al.
Publicado: (2012)

PELDOR in rotationally symmetric homo-oligomers
por: Giannoulis, Angeliki, et al.
Publicado: (2013)

Hetero/Homo-Complexes of Sucrose Transporters May Be a Subtle Mode to Regulate Sucrose Transportation in Grape Berries
por: Cai, Yumeng, et al.
Publicado: (2021)

Conformational Analysis of Charged Homo-Polypeptides
por: Bigman, Lavi S., et al.
Publicado: (2023)

Stepwise design of pseudosymmetric protein hetero-oligomers
por: Kibler, Ryan D., et al.
Publicado: (2023)

A Covalent and Modular Synthesis of Homo- and Hetero[n]rotaxanes
por: Cornelissen, Milo D., et al.
Publicado: (2020)

Comparative Transcriptome Analysis in Homo- and Hetero-Grafted Cucurbit Seedlings
por: Bantis, Filippos, et al.
Publicado: (2021)

Hetero and homo α,ω‐chain‐end functionalized polyphosphazenes
por: Strasser, Paul, et al.
Publicado: (2022)

Identification and Evaluation of Clinical Substrates of Organic Anion Transporting Polypeptides 1B1 and 1B3
por: McFeely, Savannah J., et al.
Publicado: (2019)

Tumor-Specific Expression of Organic Anion-Transporting Polypeptides: Transporters as Novel Targets for Cancer Therapy
por: Buxhofer-Ausch, Veronika, et al.
Publicado: (2013)

Human Organic Anion Transporting Polypeptide 1B3 Applied as an MRI-Based Reporter Gene
por: Baek, Song-Ee, et al.
Publicado: (2020)

The types II and III transforming growth factor-beta receptors form homo-oligomers
Publicado: (1994)

The Flavodiiron Protein Flv3 Functions as a Homo-Oligomer During Stress Acclimation and is Distinct from the Flv1/Flv3 Hetero-Oligomer Specific to the O(2) Photoreduction Pathway
por: Mustila, Henna, et al.
Publicado: (2016)

Function of homo- and hetero-oligomers of human nucleoplasmin/nucleophosmin family proteins NPM1, NPM2 and NPM3 during sperm chromatin remodeling
por: Okuwaki, Mitsuru, et al.
Publicado: (2012)

Characterization of tick organic anion transporting polypeptides (OATPs) upon bacterial and viral infections
por: Taank, Vikas, et al.
Publicado: (2018)

The involvement of human organic anion transporting polypeptides (OATPs) in drug-herb/food interactions
por: Ali, Youmna, et al.
Publicado: (2020)

Expression and Function of Organic Anion Transporting Polypeptides in the Human Brain: Physiological and Pharmacological Implications
por: Schäfer, Anima M., et al.
Publicado: (2021)

Comparative Modelling of Organic Anion Transporting Polypeptides: Structural Insights and Comparison of Binding Modes
por: Tonduru, Arun Kumar, et al.
Publicado: (2022)

Direct Homo- and Hetero-Interactions of MeCP2 and MBD2
por: Becker, Annette, et al.
Publicado: (2013)

Deamidation alters interactions of β-crystallins in hetero-oligomers
por: Takata, Takumi, et al.
Publicado: (2009)

Organic Anion Transporting Polypeptide 1B1 Is a Potential Reporter for Dual MR and Optical Imaging
por: Lee, Yi-Hsueh, et al.
Publicado: (2021)

The Double-Leucine Motifs Affect Internalization, Stability, and Function of Organic Anion Transporting Polypeptide 1B1
por: Wang, Xuyang, et al.
Publicado: (2023)

Organic anion transporting polypeptides OATP1B1 and OATP1B3 and their genetic variants influence the pharmacokinetics and pharmacodynamics of raloxifene
por: Trdan Lušin, Tina, et al.
Publicado: (2012)

Unique expression features of cancer-type organic anion transporting polypeptide 1B3 mRNA expression in human colon and lung cancers
por: Sun, Yuchen, et al.
Publicado: (2014)

Influence of Rifampin‐Mediated Organic Anion‐Transporting Polypeptide 1B1/1B3 Inhibition on the Pharmacokinetics of Clazosentan
por: Juif, Pierre‐Eric, et al.
Publicado: (2019)

The Signature Sequence Region of the Human Drug Transporter Organic Anion Transporting Polypeptide 1B1 Is Important for Protein Surface Expression
por: Taylor-Wells, Jennina, et al.
Publicado: (2014)

Organic Anion Transporting Polypeptide 2B1 in Human Fetal Membranes: A Novel Gatekeeper for Drug Transport During Pregnancy?
por: Ganguly, Esha, et al.
Publicado: (2021)

Organic Anion Transporting Polypeptide (OATP) 1B3 is a Significant Transporter for Hepatic Uptake of Conjugated Bile Acids in Humans
por: Pan, Qiong, et al.
Publicado: (2023)

Organic anion-transporting polypeptide 1B3 as a dual reporter gene for fluorescence and magnetic resonance imaging
por: Wu, Menq-Rong, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_r04drslq497i9mvum1cj40bjt1