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TRPA1 and TRPV1 contribute to propofol-mediated antagonism of U46619-induced constriction in murine coronary arteries
BACKGROUND: Transient receptor potential (TRP) ion channels have emerged as key components contributing to vasoreactivity. Propofol, an anesthetic is associated with adverse side effects including hypotension and acute pain upon infusion. Our objective was to determine the extent to which TRPA1 and/...
Autores principales: | Sinharoy, Pritam, Bratz, Ian N., Sinha, Sayantani, Showalter, Loral E., Andrei, Spencer R., Damron, Derek S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482493/ https://www.ncbi.nlm.nih.gov/pubmed/28644897 http://dx.doi.org/10.1371/journal.pone.0180106 |
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