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Network-assisted target identification for haploinsufficiency and homozygous profiling screens
Chemical genomic screens have recently emerged as a systematic approach to drug discovery on a genome-wide scale. Drug target identification and elucidation of the mechanism of action (MoA) of hits from these noisy high-throughput screens remain difficult. Here, we present GIT (Genetic Interaction N...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482495/ https://www.ncbi.nlm.nih.gov/pubmed/28574983 http://dx.doi.org/10.1371/journal.pcbi.1005553 |