Cargando…
Joint modeling of genetically correlated diseases and functional annotations increases accuracy of polygenic risk prediction
Accurate prediction of disease risk based on genetic factors is an important goal in human genetics research and precision medicine. Advanced prediction models will lead to more effective disease prevention and treatment strategies. Despite the identification of thousands of disease-associated genet...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482506/ https://www.ncbi.nlm.nih.gov/pubmed/28598966 http://dx.doi.org/10.1371/journal.pgen.1006836 |