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Ligand-induced rapid skeletal muscle atrophy in HSA-Fv2E-PERK transgenic mice

BACKGROUND: Formation of 43S and 48S preinitiation complexes plays an important role in muscle protein synthesis. There is no muscle-wasting mouse model caused by a repressed 43S preinitiation complex assembly. OBJECTIVE: The aim of the present study was to develop a convenient mouse model of skelet...

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Detalles Bibliográficos
Autores principales: Miyake, Masato, Kuroda, Masashi, Kiyonari, Hiroshi, Takehana, Kenji, Hisanaga, Satoshi, Morimoto, Masatoshi, Zhang, Jun, Oyadomari, Miho, Sakaue, Hiroshi, Oyadomari, Seiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482508/
https://www.ncbi.nlm.nih.gov/pubmed/28644884
http://dx.doi.org/10.1371/journal.pone.0179955