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Genetic landscape of extreme responders with anaplastic oligodendroglioma

BACKGROUND: The NRG Oncology RTOG 9402 trial showed significant survival benefit in patients with 1p/19q co-deleted anaplastic oligodendrogliomas (AO) who received both radiation (RT) and chemotherapy (PCV regimen) versus RT alone. Substantial separation of the survival curves was only seen after 7....

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Detalles Bibliográficos
Autores principales: Holdhoff, Matthias, Cairncross, Gregory J., Kollmeyer, Thomas M., Zhang, Ming, Zhang, Peixin, Mehta, Minesh P., Werner-Wasik, Maria, Souhami, Luis, Bahary, Jean-Paul, Kwok, Young, Hartford, Alan C., Chakravarti, Arnab, Yegnasubramanian, Srinivasan, Vogelstein, Bert, Papadopoulos, Nickolas, Kinzler, Kenneth, Jenkins, Robert B., Bettegowda, Chetan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482595/
https://www.ncbi.nlm.nih.gov/pubmed/28388591
http://dx.doi.org/10.18632/oncotarget.16773