Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells

Regulatory T cells (Tregs) are potential immunotherapeutic candidates to induce transplantation tolerance. However, stability of Tregs still remains contentious and may potentially restrict their clinical use. Recent work suggested that epigenetic imprinting of Foxp3 and other Treg-specific signatur...

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Detalles Bibliográficos
Autores principales: Garg, Garima, Nikolouli, Eirini, Hardtke-Wolenski, Matthias, Toker, Aras, Ohkura, Naganari, Beckstette, Michael, Miyao, Takahisa, Geffers, Robert, Floess, Stefan, Gerdes, Norbert, Lutgens, Esther, Osterloh, Anke, Hori, Shohei, Sakaguchi, Shimon, Jaeckel, Elmar, Huehn, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482597/
https://www.ncbi.nlm.nih.gov/pubmed/28415767
http://dx.doi.org/10.18632/oncotarget.16221

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