cAMP/PKA-CREB-BDNF signaling pathway in hippocampus mediates cyclooxygenase 2-induced learning/memory deficits of rats subjected to chronic unpredictable mild stress

To investigate the mechanism of cyclooxygenase 2 (COX2) in learning and memory impairments in rats subjected to chronic unpredictable mild stress (CUMS), meloxicam was used intragastrically to inhibit the activity of cyclooxygenase 2. Moreover, cyclooxygenase 2 over-expressing or RNA interfere lenti...

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Detalles Bibliográficos
Autores principales: Luo, Ying, Kuang, Shengnan, Li, Huan, Ran, Dongzhi, Yang, Junqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482598/
https://www.ncbi.nlm.nih.gov/pubmed/28415673
http://dx.doi.org/10.18632/oncotarget.16009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482598/
https://www.ncbi.nlm.nih.gov/pubmed/28415673
http://dx.doi.org/10.18632/oncotarget.16009

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