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MicroRNAs of the mir-17~92 cluster regulate multiple aspects of pancreatic tumor development and progression

Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy characterized by resistance to currently employed chemotherapeutic approaches. Members of the mir-17~92 cluster of microRNAs (miRNAs) are upregulated in PDAC, but the precise roles of these miRNAs in PDAC are unknown. Using genetically e...

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Detalles Bibliográficos
Autores principales:	Quattrochi, Brian, Gulvady, Anushree, Driscoll, David R., Sano, Makoto, Klimstra, David S., Turner, Christopher E., Lewis, Brian C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482626/ https://www.ncbi.nlm.nih.gov/pubmed/28415794 http://dx.doi.org/10.18632/oncotarget.16277

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