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High expression of PTBP1 promote invasion of colorectal cancer by alternative splicing of cortactin
Polypyrimidine tract-binding protein 1 (PTBP1) involving in almost all steps of mRNA regulation including alternative splicing metabolism during tumorigenesis due to its RNA-binding activity. Initially, we found that high expressed PTBP1 and poor prognosis was interrelated in colorectal cancer (CRC)...
Autores principales: | Wang, Zhi-na, Liu, Dan, Yin, Bin, Ju, Wen-yi, Qiu, Hui-zhong, Xiao, Yi, Chen, Yuan-jia, Peng, Xiao-zhong, Lu, Chong-mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482648/ https://www.ncbi.nlm.nih.gov/pubmed/28404950 http://dx.doi.org/10.18632/oncotarget.15873 |
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