Calmodulin promotes matrix metalloproteinase 9 production and cell migration by inhibiting the ubiquitination and degradation of TBC1D3 oncoprotein in human breast cancer cells

The hominoid oncoprotein TBC1D3 enhances growth factor (GF) signaling and GF signaling, conversely, induces the ubiquitination and subsequent degradation of TBC1D3. However, little is known regarding the regulation of this degradation, and the role of TBC1D3 in the progression of tumors has also not...

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Detalles Bibliográficos
Autores principales: Zhao, Huzi, Zhang, Lina, Zhang, Yongchen, Zhao, Lei, Wan, Qing, Wang, Bei, Bu, Xiaodong, Wan, Meiling, Shen, Chuanlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482662/
https://www.ncbi.nlm.nih.gov/pubmed/28422741
http://dx.doi.org/10.18632/oncotarget.16756

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