Over-expression of growth differentiation factor 15 (GDF15) preventing cold ischemia reperfusion (I/R) injury in heart transplantation through Foxo3a signaling

Ischemia reperfusion (I/R) injury which inevitably occurs during heart transplantation is the major factor leading to organ failure and graft rejection. In order to develop new therapies to prevent I/R injury, we used both a murine heart transplantation model with 24 hour cold I/R and an in vitro ce...

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Detalles Bibliográficos
Autores principales: Zhang, Yixin, Moszczynski, Lisa A., Liu, Qing, Jiang, Jifu, Zhao, Duo, Quan, Douglas, Mele, Tina, McAlister, Vivian, Jevnikar, Anthony, Baek, Seung Joon, Liu, Kexiang, Zheng, Xiufen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482674/
https://www.ncbi.nlm.nih.gov/pubmed/28388574
http://dx.doi.org/10.18632/oncotarget.16607

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