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Imaging of pH in vivo using hyperpolarized (13)C-labelled zymonic acid

Natural pH regulatory mechanisms can be overruled during several pathologies such as cancer, inflammation and ischaemia, leading to local pH changes in the human body. Here we demonstrate that (13)C-labelled zymonic acid (ZA) can be used as hyperpolarized magnetic resonance pH imaging sensor. ZA is...

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Detalles Bibliográficos
Autores principales:	Düwel, Stephan, Hundshammer, Christian, Gersch, Malte, Feuerecker, Benedikt, Steiger, Katja, Buck, Achim, Walch, Axel, Haase, Axel, Glaser, Steffen J., Schwaiger, Markus, Schilling, Franz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482723/ https://www.ncbi.nlm.nih.gov/pubmed/28492229 http://dx.doi.org/10.1038/ncomms15126

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