Genome-wide profiling of heritable and de novo STR variations

Short tandem repeats (STRs) are highly variable elements that play a pivotal role in multiple genetic diseases, population genetics applications, and forensic casework. However, STRs have proven problematic to genotype from high-throughput sequencing data. Here, we describe HipSTR, a novel haplotype...

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Detalles Bibliográficos
Autores principales: Willems, Thomas, Zielinski, Dina, Yuan, Jie, Gordon, Assaf, Gymrek, Melissa, Erlich, Yaniv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482724/
https://www.ncbi.nlm.nih.gov/pubmed/28436466
http://dx.doi.org/10.1038/nmeth.4267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482724/
https://www.ncbi.nlm.nih.gov/pubmed/28436466
http://dx.doi.org/10.1038/nmeth.4267

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