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Differential pattern of HIF-1α expression in HNSCC cancer stem cells after carbon ion or photon irradiation: one molecular explanation of the oxygen effect

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) are resistant to standard treatments, partly due to cancer stem cells (CSCs) localised in hypoxic niches. Compared to X-rays, carbon ion irradiation relies on better ballistic properties, higher relative biological effectiveness and the absen...

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Detalles Bibliográficos
Autores principales:	Wozny, Anne-Sophie, Lauret, Alexandra, Battiston-Montagne, Priscillia, Guy, Jean-Baptiste, Beuve, Michael, Cunha, Micaela, Saintigny, Yannick, Blond, Emilie, Magne, Nicolas, Lalle, Philippe, Ardail, Dominique, Alphonse, Gersende, Rodriguez-Lafrasse, Claire
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482725/ https://www.ncbi.nlm.nih.gov/pubmed/28407653 http://dx.doi.org/10.1038/bjc.2017.100

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