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IFNγ-producing CD4(+) T lymphocytes: the double-edged swords in tuberculosis
IFNγ-producing CD4(+) T cells (IFNγ(+)CD4(+) T cells) are the key orchestrators of protective immunity against Mycobacterium tuberculosis (Mtb). Primarily, these cells act by enabling Mtb-infected macrophages to enforce phagosome-lysosome fusion, produce reactive nitrogen intermediates (RNIs), and a...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482791/ https://www.ncbi.nlm.nih.gov/pubmed/28646367 http://dx.doi.org/10.1186/s40169-017-0151-8 |