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Identification of introns harboring functional sequence elements through positional conservation

Many human introns carry out a function, in the sense that they are critical to maintain normal cellular activity. Their identification is fundamental to understanding cellular processes and disease. However, being noncoding elements, such functional introns are poorly predicted based on traditional...

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Detalles Bibliográficos
Autores principales: Chorev, Michal, Joseph Bekker, Alan, Goldberger, Jacob, Carmel, Liran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482813/
https://www.ncbi.nlm.nih.gov/pubmed/28646210
http://dx.doi.org/10.1038/s41598-017-04476-0