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ATP release during cell swelling activates a Ca(2+)-dependent Cl(−) current by autocrine mechanism in mouse hippocampal microglia

Microglia cells, resident immune cells of the brain, survey brain parenchyma by dynamically extending and retracting their processes. Cl(−) channels, activated in the cellular response to stretch/swelling, take part in several functions deeply connected with microglia physiology, including cell shap...

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Detalles Bibliográficos
Autores principales: Murana, E., Pagani, F., Basilico, B., Sundukova, M., Batti, L., Di Angelantonio, S., Cortese, B., Grimaldi, A., Francioso, A., Heppenstall, P., Bregestovski, P., Limatola, C., Ragozzino, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482828/
https://www.ncbi.nlm.nih.gov/pubmed/28646166
http://dx.doi.org/10.1038/s41598-017-04452-8