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miR-15b-5p resensitizes colon cancer cells to 5-fluorouracil by promoting apoptosis via the NF-κB/XIAP axis

Drug resistance, which is closely correlated with an imbalance in apoptosis, endows colorectal cancer (CRC) with enhanced progression capacity irrespective of the treatment with therapeutics. We report that miR-15b-5p is a tumor suppressor whose level is globally decreased in CRC cells and tissues....

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Detalles Bibliográficos
Autores principales:	Zhao, Ci, Zhao, Qi, Zhang, Chunhui, Wang, Guangyu, Yao, Yuanfei, Huang, Xiaoyi, Zhan, Fei, Zhu, Yuanyuan, Shi, Jiaqi, Chen, Jianan, Yan, Feihu, Zhang, Yanqiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482850/ https://www.ncbi.nlm.nih.gov/pubmed/28646148 http://dx.doi.org/10.1038/s41598-017-04172-z

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